Victor Osimhen and Napoli teammates will be working with a new manager from Tuesday as the club has sacked head coach Rudi Garcia.
Garcia, 59, who replaced Luciano Spalletti in June, has only led the team in 16 games.
He has now been replaced by former manager Walter Mazzarri until the end of the season.
Garcia departs with the club 10 points behind league leaders Inter Milan.
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62-year-old Mazzarri previously managed Napoli from 2009 to 2013.
The Italian delivered the club its first trophy in 20 years when Napoli won the 2012 Copa Italia by beating undefeated league champions Juventus in the final.
A year later, he led them to second in Serie A – the club’s highest league position in over two decades – and secured a Champions League place.
Napoli are currently fourth in table and were beaten by 17th-placed Empoli on Sunday.